The study aimed to assess fast strain-encoded (SENC) cardiac magnetic resonance (CMR) and native T1 mapping in distinguishing between hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis. Ninety-nine patients (57 with HCM, 42 with amyloidosis) were analyzed for LV parameters, myocardial strain (global and segmental), and T1 values. HCM patients showed evenly distributed strain, while amyloidosis patients exhibited apical sparing with less impaired apical strain. T1 values were significantly higher in amyloidosis. The T1-to-basal segmental strain ratio effectively differentiated between conditions (Sensitivity = 85%, Specificity = 77%, AUC = 0.90), highlighting its potential in non-contrast CMR protocols for accurate diagnosis.
The Role of Advanced Cardiovascular Imaging Modalities in Cardio-Oncology: From Early Detection to Unravelling Mechanisms of Cardiotoxicity
Advances in cancer therapies have led to a global improvement in patient survival rates. Nevertheless, the price to pay is a concomitant increase in cardiovascular (CV) morbidity and mortality in this population. Increased inflammation and disturbances of the immune system are shared by both cancer and CV diseases. Immunological effects