The study aimed to assess fast strain-encoded (SENC) cardiac magnetic resonance (CMR) and native T1 mapping in distinguishing between hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis. Ninety-nine patients (57 with HCM, 42 with amyloidosis) were analyzed for LV parameters, myocardial strain (global and segmental), and T1 values. HCM patients showed evenly distributed strain, while amyloidosis patients exhibited apical sparing with less impaired apical strain. T1 values were significantly higher in amyloidosis. The T1-to-basal segmental strain ratio effectively differentiated between conditions (Sensitivity = 85%, Specificity = 77%, AUC = 0.90), highlighting its potential in non-contrast CMR protocols for accurate diagnosis.
Layer-Specific Fast Strain-Encoded Cardiac Magnetic Resonance Imaging Aids in the Identification and Discrimination of Acute Myocardial Injury: A Prospective Proof-of-Concept Study
This study investigated the use of layer-specific fast strain-encoded cardiac magnetic resonance imaging (fSENC) for diagnosing and prognosticating acute myocardial injury in emergency department patients. It found that global longitudinal strain (GLS) and GLSdifference (the difference between epicardial and endocardial GLS) were effective predictors, with GLS showing a high diagnostic